Computational Protein Design Scientist











We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, age, citizenship, color, religion, sex, marital status, national origin, disability status, gender identity or expression, protected veteran status, or any other characteristic protected by law.


At BASF, we create chemistry through the power of connected minds. By balancing economic success with environmental protection and social responsibility, we are building a more sustainable future through chemistry. As the world’s leading chemical company, we help our customers in nearly every industry meet the current and future needs of society through science and innovation.


We provide a challenging and rewarding work environment with a strong emphasis on process safety, as well as the safety of our employees and the communities we operate in and are always working to form the best team—especially from within, through an emphasis on lifelong learning and development.


And we are constantly striving to become an even better place to work. BASF has been recognized by Forbes Magazine as one of America’s Best Large Employers in 2021. Come join us on our journey to create solutions for a sustainable future!


Computational Protein Design Scientist (2103718)- San Diego, CA


Where the Chemistry Happens


We are seeking a professional like you to join our team.  In this role, you will be responsible for driving and supporting bioscience at BASF as part of a team of computational scientists. From agricultural traits to industrial enzymes, BASF is creating innovative products that require scientists like you to bring to bear cutting edge computational tools and methods. You will use your experience with machine learning and molecular modeling to develop and implement strategies to design and improve target enzymes. In this role, focusing on enzyme engineering activities, you will need to be well versed in protein science and computational approaches. It is also expected that you will demonstrate strong project leadership skills by managing timelines, communicating with non-specialist stakeholders, and delivering impactful results.

Qualifications - BASF recognizes institutions of Higher Education which are accredited by the Council for Higher Education Accreditation or equivalent

Formula for Success


    Applying your education background in bioinformatics, biochemistry, structural biology or related field, you will lead, set the strategy for, and execute enzyme engineering projects.

    You will routinely combine your expertise with protein design computational approaches, Python script development, and Linux-based HPC environments (both on-prem and cloud).

    Utilizing experience with sequence analysis tools (e.g., Geneious) and molecular modeling tools (Rosetta, Schrodinger, MOE, etc.) will be routine as you probe sequence-structure-function relationships.

    Your background with machine learning approaches for data driven design of proteins will be essential as you navigate projects through the Design-Build-Test-Learn cycle.

    Any prior experience with next generation sequencing data analysis will be a great resource for protein library design and analysis.

    Leveraging strong interpersonal skills, you will conceive, initiate, and lead collaborations with internal colleagues and external partners.

    Relying on proven communication skills, you will participate in the larger research community both by sharing your own results, but also by providing constructive feedback to colleagues.

Your innovative style and strong initiative will be an important aspect of tackling our most pressing research challenges.


Create Your Own Chemistry: What We Offer You


Adding value to our customers begins with adding value to you. You@BASF is the suite of benefits, perks, programs and unique opportunities we offer to support you—the whole you—in all stages of your life and career. With you@BASF, you create your own chemistry.


The total rewards that you receive as a BASF employee go way beyond a paycheck. From competitive health and insurance plans, to robust retirement benefits that include company-matching contributions, to making sure you never stop learning, we believe investing in you is investing in our success. Working for a large, global organization, you’ll have a chance to grow professionally and personally, expand your network and build a rewarding and dynamic career.


BASF provides interesting and challenging learning and development opportunities to help you make the most of your talents and your job.


A unique total offer: you@BASF

At BASF you get more than just compensation. Our total offer includes a wide range of elements you need to be your best in every stage of your life. That’s what we call you@BASF. Click here to learn more.

At BASF, we believe that people are the key to our long-term success and that talent is in everyone.
We thrive on giving you the support you need to be your best and fulfil personal ambitions…that’s how we create chemistry. #belongatBASF

About BASF

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Contact us

You have questions about your application or on how to apply in Europe? The BASF Talent Acquisition Europe team is glad to assist you.

Please note that we do not return paper applications including folders. Please submit copies only and no original documents.

Please note that we do not return paper applications including folders. Please submit copies only and no original documents.

San Diego, CA, US, 92121

BASF Corporation
REDE - Research & Development

Nearest Major Market: San Diego